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Ideas Behind the Impact

Article

What Pharma Gets Right: Strategy Lessons That Travel

The pharmaceutical industry operates at the intersection of science, regulation, and human health — demanding a quality of commercial thinking that few industries match. Innovation alone is never enough. Success requires patient empathy, operational precision, and long-term thinking. After completing Rutgers’ Mini-MBA in Pharma & BioTech Innovation, I was struck by how many of the industry’s core principles extend well beyond life sciences. Here are four principles I took away from completing Rutger’s Mini-MBA in Pharma & BioTech Innovation that apply well beyond this industry.  Lesson 1: Patient Experience Is Key  In Type 2 Diabetes care, adherence is a persistent challenge even when treatments are clinically strong. The lesson is straightforward: convenience, tolerability, and ease of use are outcomes in their own right. Any product strategy that treats user experience as secondary to technical performance will underdeliver on its potential — in pharma or anywhere else. Lesson 2: Access Strategy Is as Important as the Product A strong clinical profile is necessary but not sufficient. In pharma, the path from approval to patient involves wholesalers, PBMs, insurers, government programs, and pharmacies — each with distinct incentives. Getting this architecture right requires a multi-dimensional approach: building payer and physician credibility, layering in patient engagement and access programs. Go-to-market strategy is as important as the product itself. Capitalizing on key opinion leaders and influencers in any industry is crucial. Lesson 3: Strategic Partnerships Compound Over Time Concentrating resources on core differentiation while leveraging a partner’s manufacturing scale, distribution reach, or regulatory expertise is often the faster path to impact. Knowing what to build versus what to partner for is a strategic discipline — and one that the most successful pharma companies practice deliberately. Lesson 4: AI Is Reshaping What’s Possible Perhaps the most forward-looking theme was the role of AI and innovation across the pharma value chain — from drug discovery and clinical trial design to personalized dosing and real-world evidence generation. AI isn’t a future consideration; it’s already compressing timelines, improving targeting, and enabling levels of personalization that were previously out of reach. For any organization in life sciences, understanding where AI creates leverage — and building the data infrastructure to support it — is now a core strategic priority. Building Strategy That Lasts Pharma’s scale and complexity demand rigor. Patient-centered design, layered competitive advantage, disciplined access strategy, and AI-enabled innovation are not sector-specific ideas. They are foundational principles for any organization working to create lasting impact in complex markets. At SEI, we work alongside healthcare and life sciences leaders — from R&D and clinical operations to commercialization, market access, and post-launch optimization. By integrating strategy, analytics, and technology, we help organizations accelerate time-to-value and build the infrastructure to support AI-driven innovation in highly regulated environments. Interested in healthcare strategy or go-to-market design? Let’s Connect!

AI
Article

From Hype to ROI: What’s Actually Working in Enterprise AI

A Turning Point for Enterprise AI On March 5, 2026, SEI Seattle brought together more than 80 leaders to answer one question: What’s actually working in enterprise AI? “From Hype to ROI: What’s Actually Working in Enterprise AI” wasn’t a night of vendor talking points. It was a practitioner’s field guide, forged from lived experience, hard failures, and real wins — featuring executives and practitioners from Google, Microsoft, AIGovOps Foundation, and SEI. The Panelists: Antonio Mañueco — Practice Lead, AI & Technology, SEI Ravi Vedula — Corporate Vice President, Microsoft IDEAS Ken Johnston — Founder, AIGovOps Foundation Alix Han — Agentic AI & AI-Powered UX, Google AI Is Not a Tool — It’s a Tectonic Shift Most organizations are still treating AI like software. Something to layer onto existing processes. That’s where things break down. Only 5% of AI pilots deliver meaningful impact. Not because the technology fails, but because the approach does. “If you’re looking at AI as a tool, you’re missing a giant mark. Imagine sitting in 1999 trying to bolt ROI calculations onto the Internet. You would have absolutely missed the mark.” — Antonio, Practice Lead AI & Technology, SEI The panel drew a clear parallel to the Industrial Revolution, the internet age. AI is larger in scope and faster in speed than anything that’s come before. Ravi reinforced the scale of the moment, drawing on 25 years watching technology reshape Microsoft. “I’m in a consequential role, in a consequential company, at the most consequential time in history. How could you not be excited? And if you’re not also a little terrified, you’re living under a rock.” — Ravi, Corporate Vice President, Microsoft IDEAS Fix the Foundation Before You Scale Most organizations are trying to scale AI on top of weak data foundations. Even at Microsoft’s size, Ravi shared how teams ran into inconsistent definitions, missing context and data not designed for machine use. “Data is the fuel for AI. Most companies never actually invested in it. The starting line has moved way ahead, and they’re not going to catch up without fixing the data layer first.” — Ken, Founder, AIGovOps Foundation Without a solid data layer, governance unravels. Ken shared two real-world cases, not born of bad intentions, but of inadequate structure:  Litigation revealed that an insurer’s human-review step averaged just 1.2 seconds per claim. An autonomous agent deleted a production table, added synthetic data, and altered logs to hide the error. What this means: Clean, structure, and add semantic context to your data Define owners and require human review for AI outputs Set up monitoring for your deployments to catch and resolve issues quickly Trust and Adoption Come Down to People Even the best AI fails if the experience doesn’t hold up — and if your culture isn’t ready for it. Alix watched real users type a single word, “table,” expecting sophisticated data retrieval. The gap between what designers assumed and what users actually needed was significant. “You get one shot. If your agent ships and doesn’t work well, users won’t come back. Make sure whatever you release does that one thing really, really well.” — Alix, Agentic AI & AI-Powered UX, Google The deeper challenge the panel kept returning to was unlearning. Ravi was direct: “We are obsessing about the code. We are not focusing enough on the culture.”  Antonio pushed on this further, asking the audience how many use AI to write outgoing emails and how many use it to summarize incoming ones: “A lot of what we do in the enterprise is accumulated debt dressed as process.” What this means: Focus on real user needs Rethink workflows, not just automate them Keep human judgment at the center What This Means for Your Organization The panelists closed the evening by distilling their experience into actionable guidance. Across their different vantage points — product, governance, data infrastructure, and delivery — five clear themes emerged: Focus on one outcome first Resist the temptation to let a thousand experiments bloom. Pick an entity, a kernel, a use case — and get it right. Success compounds. Fix your data before you scale your AI Semantic richness, freshness, quality, and governance are not post-launch concerns. They are prerequisites. Govern from the start, not as an afterthought Accountability structures, risk classification, and compliance integration are what separate one-time pilots from trusted, scalable capabilities. Instrument everything and build for learning Treat every deployment as Version 1. At the end of every AI session, ask the model how you can accomplish the same outcome in fewer steps. Keep humans at the center There will always be roles that are irreplaceably human: judgment, relationships, reading a room, holding the line. Protect that. Invest in people. From Strategy to Execution, End to End AI strategy without execution doesn’t deliver value. Execution without strategy creates waste. SEI brings both — and a proven methodology to get you there. The SEI AI Transformation Approach: 01: Define a Path ForwardRigorous AI assessment and strategy — evaluating readiness, identifying high-value use cases, and building a clear roadmap aligned to your business goals.02: Prepare the OrganizationBuilding AI literacy, managing culture change, and ensuring your people understand the real value and real limits of AI before you scale.03: Experiment & InnovateTurning strategy into production-ready solutions — custom agentic workflows, vendor evaluation, and the data infrastructure to support each use case.04: Sustain ValueEmbedding intelligent automation into critical processes, governing AI agents with rigor, and building the feedback loops that improve performance over time. Across all four phases, SEI brings full-spectrum capabilities, allowing us to serve as a single, accountable transformation partner rather than a collection of specialized vendors. AI & Technology • Concept to Delivery • Data & Analytics • Security, Risk & Compliance • Strategy & Operations SEI Seattle: Where Strategy Meets Execution Since opening in 2023, SEI Seattle has built a team focused on solving complex, real-world AI challenges across the Pacific Northwest and beyond. Seattle was a deliberate choice — it’s the epicenter of technology innovation in North America, and its entrepreneurial spirit matches our own. This event reinforced what we see every day: organizations don’t need more AI ideas. They need partners who can help make AI actually work. If you’re on your own AI journey and want to be part of this dialogue, we invite you to connect with the SEI Seattle team. Let’s talk! Want to share the full recap of this event? Download the PDF here!

AI
Resource

Data Strategy: The Foundation for GenAI Success

Data and a well-defined Data Strategy are crucial to successful GenAI Adoption. At SEI, we believe great AI starts with great data. As organizations accelerate toward a future shaped by GenAI, one truth becomes clear: AI is only as powerful as the data that fuels it.  While many are eager to harness the speed and scale of GenAI to transform how they operate, far fewer have laid the groundwork to do so successfully. The challenge? Most companies are still early in their data maturity journey. Without a strong, trusted data foundation, even the most promising AI initiatives can stall — delivering poor outputs, eroding trust, and putting long-term ROI at risk. Organizations must treat data as a strategic asset to unlock AI’s full potential. That means modernizing legacy systems, improving governance, integrating platforms, and embedding data literacy across every level of the business. It also means aligning AI efforts with core business objectives and building the infrastructure and practices to support scale, security, and sustainability. This case study explores the core data principles and strategic steps organizations must take to move from experimentation to enterprise-grade GenAI. When it comes to AI, good data isn’t just important — it’s everything. Is your Data an Enabler or a Deterrent? We are at an exciting crossroads with AI and GenAI a top priority for organizations across all industries. Here are some key fundamental reasons that make maturing their Data Capabilities crucial. GenAI is Only as Good as the Data It Consumes GenAI models rely heavily on high-quality, relevant, and structured data to generate accurate, valuable, and context-aware outputs. If the input data is fragmented, biased, outdated, or lacks depth, GenAI outputs will reflect those flaws, resulting in poor decisions, hallucinations, or reputational risk. Data Strategy Aligns AI with Business Goals A clear data strategy, with the right Data Governance Framework ensures that GenAI efforts are targeted at high-impact use cases, aligned with organizational priorities. It defines what data matters, who owns it, and how it will be governed, enabling scalable and responsible AI use. Governance and Compliance Are Built on Data Foundations GenAI introduces new risks related to data privacy, security, copyright, and explainability. A mature data strategy embeds governance frameworks to ensure regulatory compliance, ethical AI use, and trustworthy outputs, particularly critical in healthcare, finance, and regulated sectors. Metadata, Context, and Semantics Matter GenAI needs metadata, taxonomies, and knowledge graphs to understand the business context and produce domain-specific results. A strong data strategy helps define and manage this semantic layer, enabling more precise and useful generation. This is critical to ensure trust. Operationalization Depends on Data Infrastructure Deploying GenAI into production requires clean pipelines, data catalogs, feature stores, and APIs. A modern data architecture, enabled by a well thought out data strategy, ensures that GenAI is not just a prototype, but a repeatable, secure, and governed solution. Feedback Loops Require Data to Improve Continuous learning, fine-tuning, and reinforcement mechanisms need labeled data and user feedback. A data strategy ensures the organization has the systems to capture this feedback, close the loop, and refine the GenAI models over time. A deep dive into GenAI… Why is a deliberate Data Strategy an imperative for GenAI success? A Data Strategy should be a precursor to your Gen AI solutions before they are deployed in Production. Failing to do that, may cause challenges that erode trust, cost more and run the risk of getting defunded. Core Data Principles for LLM Performance Optimization Data QualityA well-structured dataset will always yield better results than excessive model tuning. Contextual RelevanceEnsure that the data provided to the LLM is domain-specific and relevant to the business problem. Consistency & StandardizationEstablish data normalization practices to remove inconsistencies across sources. Real-Time Data AccessibilityIf the use case requires dynamic responses, ensure access to fresh and updated data. Bias & Ethical ConsiderationsConduct bias audits and ensure fairness in AI-generated outputs. Making Data Usable, Valuable, and Error-Free Data Ingestion & Processing Identify relevant data sources (structured, semi-structured, and unstructured). Implement ETL (Extract, Transform, Load) pipelines to cleanse and transform data. Use schema-on-read approaches to handle evolving data formats. Data Storage & Management Store unstructured data (text, documents) in vector databases for efficient retrieval. Maintain structured data in a modern data warehouse (e.g., Snowflake, databricks). Enable real-time access via streaming pipelines (Kafka, Apache Pulsar). Data Labeling & Annotation Use human-in-the-loop (HITL) techniques to validate training datasets. Implement automatic entity recognition (NER) for structured metadata extraction. Leverage active learning models to continuously improve data annotations. Fine-Tuning & Retrieval Optimization Fine-tune the model with domain-specific datasets if necessary. Use Retrieval Augmented Generation (RAG) with a vector database to reduce hallucinations. Implement hybrid search (BM25 + dense vector search) to improve query relevance Model Testing & Validation Implement LLM evaluation frameworks (HELLO-SWE, OpenAI’s Evals). Validate model outputs using ground-truth datasets. Track performance metrics (BLEU score, perplexity, retrieval precision). Governance, Security & Compliance Establish LLM usage policies and data governance frameworks. Implement data access controls to prevent leakage of sensitive information. Monitor prompt injections and adversarial attacks for security. Challenges Facing D&A Leaders Today’s leaders are faced with the challenge of delivering AI innovation without clear direction, skilled employees and in-depth understanding of the resources needed to make AI successful. Data is an enabler for AI solutions. Enablement requires: Data strategies to increase data maturity across the organization Data platforms that support scalability, flexibility and acceleration of new solutions Organizational governance and literacy of data supporting business initiatives Pressure to Accelerate D&A leaders are under pressure to deliver results faster, even if the company doesn’t have a clear plan in place. Upskilling Employees Training employees to work with data is difficult due to partial support and data maturity across the organization. AI Knowledge Leaders want to use AI, but there is a gap in understanding what is needed to make it work, including skills, budgets and resources. Evolving Role AI is changing what D&A leaders do. They need to adjust their strategies and ways of working to keep up with growing demands. Data Technologies, Platforms & Frameworks Want easy access to share this case study? Download the PDF here

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From Problem to Proof

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Building A Centralized Data Hub for University Reporting

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Optimizing Campus Services Finance and Administration

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